摘要
本组研究了70名主动脉夹层动脉瘤患者的临床特点、病因病理、影像学诊断、治疗与预后。31~70岁者占93%.男女患病率之比为3.7:1。近端型与远端型之比为0.8:1。高血压者占67%,马凡综合征占18%.病理检查表现为中层弹力纤维稀疏、断裂、粘液性变、囊性坏死。80%患者无发病诱因,76%有胸痛、69%为剧痛。胸片、超声、电子计算机断层(CT)磁共振显像(MRl)结合临床可确诊本病。超声检查敏感性为97%、特异性为94%.近端型外科与内科治疗住院病死率分别为14%与22%.远端型分别为63%与27%.死亡原因68%瘤体破裂出血。
he clinical features,etiologies,pathogenesis,treatment and prognosis of 70 patients with aortic dissecting were studied.Patients with age ranging from 31 to 70 vears consisted 93% of the total. The proportion of proximal to distal types is 0.8:1.Hypertension was present in 67 % and Marfan′s syndrome 18% of the patients. The pathologic finding was scattered rupture with myxomatous and cystic necrosis of the mecial elastic fibers. 80% of the patients suffered from the disease without anv in-ducing cause.Of the 76% patients had chest pain,it was very severe in 69%. Chest X一ray,ultrasound,computed tomography and magnetic resonance imaging together with clinical manifestations may accurately diagnose the disease. The sensitivity and specificity of the ultrasound are 97 % and 94% respectively.The mortality in hospital with surgical and medical therapy of the proximal type was 14% and 22% respectively, while that of the distal type was 63% and 27% respectively.Rupture of the aneurysm was the cause of death in 68% of the patients.
出处
《中华内科杂志》
CAS
CSCD
北大核心
1994年第6期385-387,共3页
Chinese Journal of Internal Medicine