摘要
目的分析HIV/AIDS患者结核菌素(PPD)反应及其与CD4细胞计数间的关系。方法采取前瞻性对照研究方法,对202名健康者及40例经免疫蛋白印迹法(WB)确证的HIV/AIDS病人进行PPD试验、CD4、CD8淋巴细胞计数。结果HIV/AIDS患者中PPD阳性率12.5%,健康对照PPD阳性率28.2%(P<0.05)。CD4细胞计数<200/mm3者,PPD均为阴性。CD4/CD8比值<1者达90%。结论HIV/AIDS患者机体免疫力降低,PPD反应明显下降。在确诊HIV/AIDS患者并发结核病时应值得注意。
Objective To analyze relation between purified protein derivative PPD skin test result and CD_4 cell count in HIV/AIDS positive patients.Methods The prospective study was applied.PPD,CD_4 and CD_8 cell counts were examined between 202 health and 40 HIV/AIDS patients confirmed by western blot.Results 12.5% of HIV/AIDS patients was PPD positive,meanwhile,28.2% of health was PPD positive,(P<0.05).All of the CD_4 Cell count below 220/mm3 was PPD negative,the CD_4/CD_8 below 1 accounted for 90%.Conclusion PPD reaction decreases dramatically with the descending of immunity of HIV/AIDS patients.It is caused attention to diagnose tuberculosis in HIV/AIDS patients.
出处
《中国公共卫生》
CAS
CSCD
北大核心
2005年第6期677-678,共2页
Chinese Journal of Public Health
基金
河南省科技攻关项目(0224630022)
中国疾病预防控制中心资助项目
关键词
艾滋病病毒
艾滋病
结核分枝杆菌
结核菌素
HIV/AIDS
mycobacterium tuberculosis
purified protein derivative(PPD)
