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局部肌瓣转移和自体红骨髓注射治疗胫骨骨折骨不连 被引量:6

Treatment of nonunion of tibial fractures with local muscle flap transfer and injection of autogenous bone marrow
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摘要 目的报告局部转移肌瓣和注射自体红骨髓治疗胫骨骨折不连接的效果。方法对15例伤后10~42个月,平均22个月仍不连接的胫骨骨折实施切开复位、带锁髓内钉固定、髂骨植骨和局部转移肌瓣覆盖,术后12~15d局部注射自体红骨髓治疗。结果随访表明所有病例骨折均得到连接,术后3~11个月(平均4.8个月)愈合,除2例术后出现切口皮缘小块坏死经换药愈合外,创口均一期愈合,没有发生感染和内固定失败。结论在稳固内固定和植骨以外,局部转移肌瓣和注射自体红骨髓治疗胫骨骨折不愈合能取得满意疗效。 Objective To report the treatment outcome of nonunion of tibial fractures with local muscle flap transfer and injection of autogenous bone marrow. Methods 15 patients who had suffered from nonunion of tibial fracture 10 to 42 (mean 22) months after the initial injury underwent open reduction, internal fixation with locking intramedullary nail, wound coverage with locally transferred muscle flap and injection of autogenous bone marrow into the fracture site 12 to 15 days after operation. Results The follow-ups revealed bone union in all the cases of this series with a mean healing time of 22 (3 to 11) months. Except for limited necrosis of the skin edge in 2 cases which healed after dressing changes, the wounds healed primarily in all the cases without infection and implant failure. Conclusion Besides stable internal fixation and bone graft, coverage of fracture site with locally transferred muscle flap and injection of autogenous bone marrow can be used to treat nonunion of tibial fractures with satisfactory results.
出处 《中华创伤骨科杂志》 CAS CSCD 2005年第5期412-414,共3页 Chinese Journal of Orthopaedic Trauma
关键词 胫骨 骨折 骨不连 自体骨髓 Tibia Fracture Nonunion Autogenous bone marrow
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  • 1王瑞旻 李亚非 蔡晓峰 苏正曙.带蒂肌瓣转移与经皮注射自体红骨髓治疗胫骨 C型骨折[J].中国矫形外科杂志,2001,8:310-310.
  • 2何飞,黄河,龚跃昆,李世和.交锁髓内钉治疗下肢长管状骨骨折不愈合及延迟愈合[J].中华创伤骨科杂志,2004,6(2):136-137. 被引量:32
  • 3Shepherd LE, Costigan WM, Gardocki RJ, Ghiassi AD, Patzakis MJ, Stevanovic MV. Local or free muscle flaps and unreamed interlocked nails for open tibial fractures. Clin Orthop, 1998,(350):90-96.
  • 4马真胜 . 骨与软骨损伤的修复 . 见:付小兵 ,王德文,主编 .现代创伤修复学 . 第 1版 .北京:人民军医出版社, 1999.375-488.
  • 5Welch RD, Jones AL, Bucholz RW, Reinert CM, Tjia JS, Pierce WA, Wozney JM, Li XJ. Effect of recombinant human bone morphogenetic protein-2 on fracture healing in a goat tibial fracture model. J Bone Min Res, 1998, 13:1483-1490.

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