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Toll样受体与支气管哮喘免疫调控 被引量:18

Toll-Like Recepters and Immune Regulation in Asthma
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摘要 Toll样受体 (TLRs)是一种属于I型跨膜蛋白的天然免疫模式识别受体。近年来发现TLRs参与多种媒介组分的识别 ,且TLRs信号激活通过转接蛋白MyD88和 /或TIRAP/Mal依赖性通路诱导树突细胞成熟、促进T细胞分化和调节肥大细胞反应 ,成为联系天然免疫和适应性免疫的桥梁 ,从而在哮喘免疫调控中起重要作用。
出处 《国外医学(儿科学分册)》 2005年第2期92-95,共4页 Foreign Medical Sciences(Section of Pediatrics)
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