摘要
以苯海拉明与碘的分子缔合物为电活性物的涂碳式 PVC膜苯海拉明选择电极。测定了盐酸苯海拉明片的含量。电极的线性响应范围 3 .2× 10 - 2 ～ 2 .6× 10 - 5mol/L ,级差电位为 2 9m V/p C,检测限为 1.6× 10 - 5mol/L。该电极响应迅速 ,重现性好 ,方法简便 ,结果与药典法相符。
In this paper, a new coated carbon polyvinyl chloride membrane diphenhydramine selective electrode based on diphenhydramine and iodine molecular association complex is reported. The electrode showed Nernst response for diphenhydramine ranges between 3.2×10 -2～2.6×10 -5mol/L with a slope of 29 mV/pC. The detection limit is 1.6×10 -5mol/L. The electrode has fast response and good reproducibility. The electrode has been used for the determination of diphenhydramine in medicinal tablets by the standard curve method. The procedure of this method is simple and the reseuts obtained agree with those of pharmacopeial method.
出处
《数理医药学杂志》
2005年第2期174-175,共2页
Journal of Mathematical Medicine
关键词
涂碳式
聚氯乙烯膜
电极
苯海拉明
回收率
Ion\|selective electrode
diphenhydramine
coated carbon
determination
