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立体定向放射(体部伽玛刀)治疗原发性肝癌的疗效分析 被引量:24

The Clinical Study of Whole Body γ-Knife for Primary Hepatocellular Carcinoma
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摘要 目的 分析体部伽玛刀治疗肝癌的效果。方法 设备为OUR QGD型立体定向体部伽玛射线放 射治疗系统。处方等剂量线采用55%~70%等剂量包饶计划靶区;一般剂量每次2.8~5Gy,治疗次数为8~ 13次,总放射剂量30.8~50Gy;每天或隔天伽玛刀治疗。结果 治疗后3个月总的有效率为81.0%(123/ 152),6个月总的局部控制率及生存率分别为63.2%(96/152)、66.5%(101/152);1年总的局部控制率及生 存率分别为39.4%(37/94)、41.5%(39/94)。结论 采用伽玛刀对肝癌进行治疗,疗效比较满意,说明伽玛刀 对肝癌是较好的局部治疗方式。副作用轻,随访期内未见严重放射性并发症。 Objective To study the therapeutic effect of whole body γ-knife for primary hepatocellular carcinoma. Methods From January 2002 to October 2003, 152 patients with primary hepatocellular carcinoma were treated by whole body γ-knife. The lesions of 39 patients were ≤5 cm, the lesions of 91 patients were >5 cm、≤10 cm, the lesions of 22 patients were >10 cm. Dosage of 2.8~5 Gy/fraction (8~13 fractions) was used for the patients, the total doses were 30.8~50 Gy. 55%~70% isodose include 95% PTV. Results The total effective rate was 81.0% three months after treatment. The 6-months local control rates and 6-months survival rates were 63.2% and 66.5% respectively. The 1-year local control rates and 1-year survival rates were 39% and 41% respectively. Serious complications of radiotherapy were not seen. Conclusion Whole body γ-knife is useful for the primary hepatocellular carcinoma.
出处 《海军总医院学报》 2005年第1期16-19,共4页 Journal of Naval General Hospital of PLA
关键词 原发性肝癌 全身伽玛刀 Primary hepatocellular carcinoma Whole body γ-knife
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参考文献5

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二级参考文献18

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