摘要
目的 :探讨硫普罗宁、还原型谷胱甘肽联合复方丹参注射液治疗早期肝硬化疗效。方法 :诊断为早期肝硬化患者 5 9例 ,随机分为两组 ,观察组 32例给予硫普罗宁 2 0 0mg、还原型谷胱甘肽 1.2g、复方丹参注射液 2 0ml静脉点滴 ,每日 1次 ,疗程 6周 ;对照组 2 7例进行常规支持治疗。观察治疗后两组的临床症状改善、肝功、血清纤维化指标及腹部超声影像的变化并进行比较。结果 :两组各项指标与治疗前比较均有改善 (P <0 .0 5 ) ,两组比较观察组疗效优于治疗组(P <0 .0 5 )。结论 :硫普罗宁、还原型谷胱甘肽联合复方丹参注射液治疗早期肝硬化是一种有效的治疗方法。
Objective:To investigate the Curative Effect of Treatment of Patients with Cirrhosis in Early Stage with Tiopronin and Glutathione combined Compound Salvia Miltiprrhiza Injection. Methods: 59 cases Cirrhosis in early stage were randomly divided into two groups, 32 cases in observation group were given 200mg Tiopronin, 1.2g Reduced Glutathione and 20ml Compound Salvia Miltiprrhiza Injection with intravenous instillation, once a week and for 6 weeks. The control group with 27 cases was given routine support treatment. The improvement of clinical symptom, the liver function, the index of serum fibrosis and the change of the abdomen ultrasonic image of the two groups after treatment were studied and compared. Results:The index of the two groups had improved than that before treatment. The curative effect of the observation group was superior to that of the control group (P<0.05). Conclusion:Tiopronin and Reduced Glutathione combined Compound Salvia Miltiprrhiza Injection is an efficient method to treat Cirrhosis in Early Stage.
出处
《四川省卫生管理干部学院学报》
2004年第4期253-255,共3页
Journal of Sichuan Continuing Education College of Medical Sciences
关键词
硫普罗宁
肝纤维化
氧自由基
复方丹参
Tiopronin
Liver fibrosis
Oxygen free radicals
Compound Salvia Miltiprrhiza
