摘要
本文采用３Ｈ－ＴｄＲ掺入法，进行了脾细胞增殖效应的实验，观察了珠子参总皂甙体内外给药时及不同浓度时，对有丝分裂原所诱发的淋巴细胞增殖效应的影响．结果表明：珠子参总甙对ＰＨＡ和ＣｏｎＡ诱导下的Ｔ细胞增殖效应有明显的增强作用，而对ＬＰＳ诱导下的Ｂ细胞增殖效应无明显增强作用，其浓度的高低也影响着Ｔ细胞增殖反应的增强作用．结合以往的研究，进一步证实了珠子参的免疫药理作用是多方面的，尤其是有复杂的免疫调节性能．本文为珠子参的临床应用提供了实验依据．
Spleen cell proliferation effect with 3H-TdR perneating assy was reported in the paper.Effect of Panax Japonics Saponin on lymphocyte proliferation induced by proliferation mitoggen was observed.The results showed that panax japonics saponin obviously enhanced T lymphocyte proliferation induced by PHA and Con A. But no obviously enhanced B lymphocyte proliferation induced by LPS and its concentration influence on T lymphocyte proliferation was noted.It suggested that the immunopharmacologic effect of panax japonics saponics were various and complex. It offered an experimental evidence for clinical applying.
出处
《昆明医学院学报》
1994年第1期65-67,共3页
Journal of Kunming Medical College
基金
云南省应用基础研究基金
关键词
珠子参
皂甙
脾细胞
增殖效应
Panax Japonicus Saponin Tlymphocyte Proliferation mitogene Blymphocyte Respons on spleen lymphocyte
