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5′-核苷酸磷酸二酯酶同工酶鉴别良恶性腹水的诊断价值

The Diagnostic Value of 5'-Nucleotide Phosphodiesterase Isoenzyme in Differentiating Malignant from Unmalignant Ascites
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摘要 对37例恶性腹水和35例良性腹水测定5′-NPD同工酶,结果表明:恶性腹水中5′-NPI)-Ⅴ和Ⅵ的阳性率明显高于良性腹水(P<0.01)。特异性分别为80%和74.3%;腹水5′-NPD-Ⅴ与血清相关性γ=0.7804(P>0.05)。提示:腹水5′-NPD同工酶检测有助于良恶性腹水鉴别诊断。在疑恶性腹水时有必要进行腹水5′-NPD同工酶检测。 5'-nucleotide phosphodiesterase (5'-NPD) isoenzyme was measured in 37 cases with malignant ascites (MA) and 35 cases with unmalignant ascites (UMA). The positive rate of 5'-NPD-Ⅴ and Ⅵ in MA were significantly higher than that in UMA(P<0.01). The correlation of 5'-NPD-Ⅴ in ascites and serum r=0.7804(P<0.05). The data sugested that :1. The estimation of 5'-NPD isoenzyme in ascitec fluids is of important value for differentiating MA from UMA. 2. The estimation of 5'-NPD isoenzyme in ascitic fluid differ from that in serum. It is nessessory that 5'-NPD isoenzyme in ascitic fluid be measured, when MA was suspected.
出处 《中国医科大学学报》 CAS CSCD 1993年第6期444-446,共3页 Journal of China Medical University
关键词 核苷酸 磷酸二酯酶 腹水 肝肿瘤 5′-nucleotide phosphodiesterase 5′-mucleotide phosphodiesterase (5′-NPD) ascites primary hepatic cancer gastric cancer tuberculous peritonitis hepatic cirrhosis
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参考文献1

  • 1Lin K M,Int J Cancer,1986年,37卷,849页

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