摘要
目的:评价药物涂层支架在冠状动脉长病变内(病变长度≥20 mm)的临床疗效。方法:对 50 例冠心病患者行药物涂层冠状动脉内支架治疗(56只,药物长支架组),随机选择同期50例接受普通支架治疗(52 只,普通长支架组),比较两组支架置入情况及临床事件发生率。结果: 两组手术成功率相似(100% ∶98.0%, P>0.05)。平均随访(7.6±2.1) 个月,随访率85%,药物长支架组心绞痛复发率显著低于普通长支架组(6.82% ∶19.51%,P<0.05)。结论:冠心病患者应用药物涂层支架治疗长病变临床效果优于普通支架。
Objective:To evaluate the efficacy of coronary drug-eluting stent(DES) in patients with coronary artery disease(CAD). Method:From July 2003 to December 2003,50 patients were treated with long coronary drug-eluting stents(DES group).The follow-up outcomes of these patients were compared with another 50 well-matched cases who received standard uncoated stents(Control group) within the same time period.Result:Baseline clinical characteristics were similar between the two groups except that there were more diabetes mellitus in the DES group.Angiographic success rate(100%∶ 98.0%, P> 0.05) and stenting procedure were comparable in the two groups.During mean 7.6 months of follow-up, the rate of recurrent angina pectoris was significantly lower in the DES group than that in the control group( 6.82%∶ 19.51%, P< 0.05). There were no major cardiovascular events in the two groups. Conclusion:As compared with standard uncoated long coronary stent, long coronary drug-eluting stent provides better clinical efficacy.
出处
《临床心血管病杂志》
CAS
CSCD
北大核心
2005年第2期87-89,共3页
Journal of Clinical Cardiology