摘要
目的考察我室研制的软膏剂猪皮生物敷料对大鼠深二度烧伤创面的愈合作用。方法利用SPF级SD大鼠制备深二度烧伤动物模型,以灭菌油纱布敷料为对照组,观察利用软膏剂猪皮生物敷料对创面愈合作用的影响。结果实验组创面覆盖后渗出明显减少,愈合时间平均为213d,愈合时间较对照组提前了59d。实验组伤后7、9、12、15、18及21d的创面愈合率较烧伤对照组高(P<001)。结论软膏剂猪皮生物敷料促进烧伤创面愈合,对于临床上需要包扎的创面,这种膏剂猪皮敷料是一种很好的选择。
Objective To study curative effect of pig_skin biological dressing (made into the ointment ) on the rats of deep Ⅱ degree burning surface. Method\ Animal models of deep Ⅱ degree burning surface were made in SD rats of SPF grade. With vaseline gauze as a control group, curative effects of pig_skin dressing on rat burning surface were observed. Result\ The time of wound healing was 5 9 days earlier in pig_skin biological dressing than vaseline gauze, the percentage of wound healing at 7,9,12,15,18 and 21 days after burn was higher in the experiment group than that in the blank group ( P <0 01). Conclusion This ointment can improve the healing of burning surface. It might be a good dressing for treating burning surface.
出处
《中国比较医学杂志》
CAS
2004年第6期336-338,共3页
Chinese Journal of Comparative Medicine
