摘要
目的 :比较利培酮和氯氮平对精神分裂症患者认知功能的影响。 方法 :对 5 8例精神分裂症患者随机分成两组 ,分别给予利培酮、氯氮平治疗 8周。治疗前和治疗 8周末分别进行简明精神病评定量表 (BPRS)、韦氏成人记忆量表修订本 (WMS RC)、威斯康星卡片分类测验 (WCST)和数字划销测验(CT)评定 ,比较利培酮和氯氮平对精神分裂症患者认知功能的影响。 结果 :两组 8周后 ,各项检查项目均有显著好转。 结论 :利培酮和氯氮平均能改善精神分裂症患者的认知功能。
Objective:To compare the effects between risperidone and clozapine on cognitive function in schizophrenics. Method:Fifty-eight cases of schizophrenia patients were randomly divided into two groups and treated with resperidone or clozapine for 8 weeks.The effects on cognitive function of schizophrenia patients were evaluated separately with brief psychiatric rating scale (BPRS),WMS-RC,WCST and CT before and after treatment. Results:The total score of every test was significantly improved after treatment with risperidone or clozapine, but no significant differences were found between two groups. Conclusion:Both risperidone and clozapine can improve the cognitive function in schizophrenic patients.
出处
《临床精神医学杂志》
2005年第1期21-22,共2页
Journal of Clinical Psychiatry
关键词
利培酮
氯氮平
精神分裂症
认知功能
risperidone
clozapine
schizophrenia
cognitive function
