摘要
目的评价根治术前化疗栓塞对肾癌预后的影响.方法对26例经术后病理证实并获随访的肾癌患者临床资料进行回顾性分析,分A、B两组,肾癌根治术前化疗栓塞组16例(A组),单纯根治术组10例(B)组.A组经肾动脉灌注化疗药物后,用碘油和化疗药物混合剂行末梢血管栓塞,用明胶海绵进行中心性栓塞,化疗栓塞后2～5d行患肾根治术性切除.结果 A组术中出血量150～500ml,平均220ml;少于B组.A组1、3、5年生存率分别为86.6%、72.7%、58.1%,两组比较,差别均有显著性意义(P＜0.05).Cox模型分析表明,根治术前化疗栓塞是影响肾癌预后的独立因素.结论肾癌根治术前化疗栓塞安全有效,对肾癌的治疗有积极意义.
Objective To evaluate the prognostic efficacy of preoperative transarterial chemo-embolization for renal cell carcinoma. Methods A total of 26 cases of renal cell carcinoma confirmed by operation and pathology were retrospective studied, 16 cases were allotted to preoperative transarterial chemo-embotization and 10 cases by operation alone. Preperative transarterial chemo-embolizotion was perfomed by infusing anticaner drugs, followed by emnulsion of iodized ail and anticancer drugs for peripneral vessels embolization and then by infeeting gelation sponger into the renal artery.Surgery was perfrmed within 2～5days after transarterial chemo-embolization.Results Preoperative transarterial chemo-embolization made vesection easier. The 1,3,5 year survival of chemo-embolization group was higher than the operation alone group (P<0 05). The Cox model analysis showed preoperative transarterial chemo-embolization was an independent factor affecting the long term survival rate of renal cell carcinoma. Conclusion Preoperative transarterial chemo-embotization is a safe and effective method in the treatment of renal cell carcinoma.
出处
《现代肿瘤医学》
CAS
2005年第1期89-90,共2页
Journal of Modern Oncology
关键词
肾肿瘤
癌
化学栓塞
renal carcionoma
chemo-embolism
