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复方芦荟抑制小鼠S180荷瘤的实验研究 被引量:8

Experimental study on compound aloe inhibiting S _(180) sarcoma in mice
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摘要 目的:探讨复方芦荟对小鼠S180荷瘤的抑制作用及免疫学改变。方法:25只小鼠随机分为3组,将S180瘤细胞接种于小鼠左前肢腋窝皮下,3d后各组小鼠分别灌胃服用复方芦荟液、环磷酰胺和生理盐水,8d后计算抑瘤率,测定小鼠免疫功能的改变。结果:复方芦荟抑瘤率为69%;免疫功能测定T淋巴细胞增殖反应和NK细胞活性分别为(0.87±0.05)A和(73.18±5.58)%;环磷酰胺组分别为(0.58±0.06)A和(44.87±5.29)%;生理盐水组分别为(0.72±0.05)A和(50.03±6.12)%;两组与生理盐水组比较有显著性差异(P<0.01)。结论:复方芦荟具有抑制小鼠S180荷瘤的作用,并能提高机体免疫功能。 Objective:To study the inhibition of compound aloe from S 180 sarcome in mice and the immune change.Methods:Twenty five mice were randomly divided into 3 groups.All mice were vaccinated with S 180 sarcome cells in armit of the left forearm and 3 days later the mice were respectively given compound aloe solution,cyclophosphamide and normal saline by stomach perfusion,and 8 days later inhibition rate and change of immune functionwere detected.Results:The inhibition rate was 69 % in the compound al...
出处 《第四军医大学吉林军医学院学报(86813X)》 2000年第4期195-198,共4页 Journal of Jilin Military Medical College Fourth Military Medical University
关键词 小鼠 复方 荷瘤 S180 生理盐水 抑瘤率 芦荟 接种 显著性差异 机体免疫功能 compound aloe cyclophosphamide S _(180) sarcome immune function mice
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