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经单鼻孔-蝶窦入路显微手术切除垂体腺瘤的理论与实践 被引量:19

Theory and practice of endonasal transsphenoidal approach for microsurgical removal of pituitary adenomas
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摘要 目的探讨经单鼻孔-蝶窦入路显微手术切除垂体腺瘤的科学性和实用技术技巧。方法手术治疗42例大型、巨大型腺瘤,分析手术技术的改进和所遇到的问题,结合文献讨论技术要点。结果肿瘤全切除32例,次全切除4例,大部切除5例,部分切除1例。36例出现术后尿崩,个别出现迟发性鼻腔出血。结论经单鼻孔入路属于新型微创手术,虽然通道狭小,但只要操作适当,不论鼻孔大小均可安全实施手术,但要注意鼻腔的止血和定位的准确性。 Objective To explore the scientificity and techniques of endonasal transsphenoidal approach for microsurgical removal of pituitary adenomas. Methods 42 cases of large and giant pituitary adenomas were performed with microsurgical operations. The problems during the surgeris and technical improvement were analyzed, especially the operative details being discussed with the reviews of the relevant literatures. Results Total removal of the tumor was achieved in 32 cases, subtotal removal in 4, most removal in 5 and partial removal in 6. Diabetes insipidus appeared in 36 cases (85.7%), and delayed epistaxis in occasional cases. Conclusion Endonasal approach is a new surgical method with minimal invasiveness. Despite the narrow channels provided by nostril size, it can still be safely adopted just under proper manipulation. Hemostasis of nasal cavity and accurate location of deep structures should be noticed.
出处 《中华神经医学杂志》 CAS CSCD 2005年第1期41-43,共3页 Chinese Journal of Neuromedicine
基金 福建省自然科学基金资助项目(C0110027)
关键词 蝶窦入路 显微手术切除 垂体腺瘤 肿瘤 鼻腔出血 手术技术 迟发性 大小 通道 Pituitary neoplasms Microsurgery Transsphenoidal approach Direct endonasal approach
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参考文献6

  • 1GriffithHB, VeerapenR. A direct transnasal approach to the sphenoid sinus[J]. J Neurosurg, 1987, 66(1): 140-142.
  • 2Edal AL, Skjodt K, Nepper-Rasmussen HJ. SIPAP - a new MR classification for pituitary adenomas. Suprasellar, infrasellar,parasellar, anterior and posterior [J]. Acta Radiol, 1997, 38 (1):30-36.
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  • 6詹升全,李昭杰,林志俊,许作奎,林晓风,李贵福,舒航,周东,唐凯.神经内镜在脑外科的临床应用[J].中华外科杂志,2002,40(3):187-190. 被引量:37

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