摘要
目的:对胸腺切除术治疗重症肌无力患者的围手术期管理进行总结。方法: 365例重症肌无力患者采用经前胸第二肋间横断胸骨小切口行胸腺切除术。术前口服皮质类固醇、胆碱酯酶抑制剂改善肌无力症状,处理并发症;术中彻底清扫胸腺及前纵隔脂肪;术后继续应用胆碱酯酶抑制剂,加强呼吸道管理。结果: 329例患者安全渡过围手术期; 36例发生术后危象,其中治愈 28例,自动出院 5例,死亡 3例。结论:规范合理的围手术期处理可保证MG手术安全性,提高手术疗效,降低病死率。
Aim: To summerize the perioperative management of thymectomy for myasthenia gravis(MG).Methods: A total of 365 cases of MG treated with thymectomy by sternum transverse in second spatium intercostale incision were orally administrated corticosteroids before the surgery, and cholinesterase inhibitor before and after the surgery.Results: A total of 329 patients survived the perioperative period.Thirty six developed myasthenic crisis, among whom 28 were cured, 5 were out of the hospital, and 3 died.Conclusion: Standardized perioperative management may ensure the safety of thymectomy.
出处
《郑州大学学报（医学版）》
CAS
北大核心
2005年第1期11-13,共3页
Journal of Zhengzhou University(Medical Sciences)
基金
国家自然科学基金资助项目 39970264
河南省 2002年度杰出青年科学基金资助项目 0212000100
