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纳洛酮试验在急性脑梗死溶栓治疗前的应用价值探讨

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摘要 目的　探讨纳洛酮试验在急性脑梗死溶栓治疗前的应用价值。方法　 33例急性脑梗死患者溶栓治疗前进行纳洛酮试验 ,观察静脉溶栓前后神经功能变化 ,同时观察颅内出血的副作用。结果　纳洛酮试验神经功能缺损评分减少 8分的 2 5例为A组 ,减少不足 8分或评分增加的 8例为B组 ,A组神经功能缺损评分溶栓治疗前(2 4 6 0± 5 2 0 )分 ,治疗后 (5 10± 3 2 0 )分 (P <0 0 1) ,而B组溶栓治疗前 (2 3 90± 4 2 0 )分 ,治疗后 (18 70± 6 2 0 )分 (P >0 0 5 ) ;A组发生颅内出血 1例 ,B组发生 3例 (P <0 0 1)。结论　纳洛酮试验阳性患者溶栓治疗疗效好 ,且颅内出血机率小 。
作者 杨明 肖秋景 陈清泉
机构地区 四川省渠县人民医院 四川省渠县有庆中心卫生院
出处 《中国实用内科杂志》 CAS CSCD 北大核心 2005年第1期72-73,共2页 Chinese Journal of Practical Internal Medicine
关键词 溶栓治疗 纳洛酮 颅内出血 治疗后 神经功能缺损评分 急性脑梗死 应用价值 结论 目的 变化
分类号 R743 [医药卫生—神经病学与精神病学] R542 [医药卫生—心血管疾病]
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参考文献8

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中国实用内科杂志
2005年 第1期

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