摘要
目的探讨骨髓增生异常综合征难治性贫血与慢性再生障碍性贫血的鉴别要点,为临床诊断治疗病人提供可靠依据。方法对15例骨髓异常增生综合征难治性贫血(MDS-RA)与36例慢性再生障碍性贫血(CAA)的血象及骨髓象进行比较和分析。结果CAA组出血及三系减少的发生率明显高于MDS-RA组;骨髓细胞学检查显示,CAA组增生程度低下以及巨核细胞减少和消失的发生率明显高于MDS-RA组,而MDS-RA组病态造血的发生率则明显高于CAA组。结论骨髓细胞学检查是骨髓增生异常综合征难治性贫血与慢性再生障碍性贫血鉴别的主要手段,骨髓病理学检查能提高病态造血的检出率,尤其是ALIP检测不仅为MDS-RA和CAA鉴别的主要指标,而且能够预测疾病的预后。
Objective The purpose of abstract Analyze the distinguishable main point of the MDS-RA and the CAA,in order to provide the dependable evidnce for cure patients and clinical diagnosis.Methods Com-pare the blood figures and marrow figures on both15examples of the MDS-RA and36cases of the CAA.Results Incidence of bleeding and pancytopenia in patients with CAA were significantly higher than in MDS-RA,but the rate of hypocellular and megkaryocytopenia in bone marrow of the patients with MDS-RA were significantly lower than that in CAA,and the incidence of dysplastic hematopoiesis inbone marrow is sihnifi-cantly higher than in CAA.Conclusions The cellularity,number of megakarocytes and dysplastic hematopoiesis in bone maeeow are key differential in dexes between MDS-RA and CAA,and bone marrow biopsy may facilit-dte the measure of dysplastic hematopoiesis.
出处
《海南医学》
CAS
2005年第2期116-116,107,共2页
Hainan Medical Journal
