摘要
瘦素受体 (LeptinReceptororob R)通过与瘦素结合发挥调节机体能量代谢和体脂平衡的作用。瘦素受体在体内分布广泛并与肥胖密切相关。本文综述了瘦素受体基因结构的研究进展 ,并分析了瘦素受体与肥胖的发生、治疗等关系。
Leptin receptor plays an important role in the modulation of energy metabolism and lipid equilibrium after binding with Leptin. Leptin receptor locates widely in the human tissues and is closely linked with obesity. This manuscript reviews the structure of leptin receptor gene and its relationship with obesity, and discusses the role of leptin receptor in obesity development and therapy.
出处
《中国药理学通报》
CAS
CSCD
北大核心
2004年第12期1334-1336,共3页
Chinese Pharmacological Bulletin
关键词
瘦素受体
基因
肥胖
治疗
leptin receptor
gene
obesity
treatment