摘要
目的 探讨兼具蒿属花粉症和植物类食物过敏的患者两类变应原及其诱发症状之间的临床关系。方法 对 1999年 8月至 2 0 0 1年 9月连续诊断为蒿属花粉症伴植物类食物过敏的 5 0例患者 (男 2 1例 ,女 2 9例 ;其中 2例仅对蒿属花粉致敏 )进行观察。蒿属花粉症的诊断依据为 :有明确的夏秋季呼吸道发病的病史 ,并经蒿属花粉皮内试验和体外检测证实 ;对植物类食物过敏的诊断依据为 :有明确的进食植物类食物于 2h内出现症状的病史 ,并经皮肤点刺试验 ,部分经体外检测证实。结果 5 0例中蒿属花粉症患者的平均发病年龄为 2 4岁 (7～ 5 6岁 ) (2例仅对蒿属花粉致敏未计入内 ) ,出现植物类食物过敏症状者的平均发病年龄为 2 4岁 (3～ 5 7岁 )。 4 8例患者中 ,2 4例 (5 0 % )花粉症发病先于食物过敏 ,14例 (2 9% )食物过敏先于花粉症出现 ,同时出现症状者 10例 (2 1% )。致敏食物主要为豆科植物、桃、葵花籽、花生等。从症状看 ,吸入花粉诱发者 ,以鼻症状为主 ,占 96 % (46 / 4 8) ,接着是眼炎和哮喘 ,荨麻疹不常见 ,过敏性休克和胃肠道症状罕见。进食蔬菜、果类诱发者则以荨麻疹和口腔症状多发 ,分别占 6 6 % (33/ 5 0 )和 4 0 % (2 0 / 5 0 ) ,接着是哮喘 ,鼻炎和眼炎 ,出现过敏性休克和胃肠道症状者远较蒿属花?
Objective To study the patients with both artemisia pollenosis and plant food allergy. Methods The diagnosis of artemisia pollenosis was based on a history of summer autumn pollenosis, and positive intradermal test with artemisia pollen (Ar) and serum specific IgE Ar; the diagnosis of plant food allergy was based on a history of the symptoms occurred shortly after the intake of some plant foods, and positive skin prick test using some plant food, and positive specific IgE in some of them. Results A total of 50 patients with both artemisia pollenosis and plant food allergy was diagnosed. The average age of onset of artemisia pollenosis was 24 (7～56 yr),The average age of onset of allergy to plant food was 23 year 8 month (3～57 yr). Sex ratio (M:F) was 21:29 with female predominating.artemisia pollenosis occurred prior to food allergy in 50 % of the patients, plant food allergy occurred prior to pollenosis in about 29% of the patients,both of them occurred simultaneusly in 21%. The common offending food were legumes,peach and peanut and sunflower seeds etc, nasal symptoms by inhalation of Ar occurred in 96%(46/48) of the patients, followed by conjunctivitis and asthma,urticaria was not common,anaphylatic shock and gastrointestinal symptoms were rare. The common clinical manifestations caused by ingestion of plant food were urticaria and oral allergy syndrome (OAS) occurred in 66%(33/50) and 40%(20/50) of the patients respectively, followed by asthma, rhinitis and conjunctivitis, anaphylactic shock and gastrointestinal tract symptoms were much more frequently than artemisia pollenosis. but single oral mucosa symptoms only occurred in 3 patients.Conclusion The patients with pollenosis must be in vigilance for the development of plant food allergy later,and vise versa. Single oral mucosa symptoms were rarely seen.
出处
《中华医学杂志》
CAS
CSCD
北大核心
2002年第9期626-629,共4页
National Medical Journal of China
