摘要
研究姜黄素诱导肿瘤细胞凋亡的可能机制 ,利用 fluo-4/AM荧光钙离子探针测定 BGC-82 3细胞与MCF-7细胞经姜黄素处理后的钙波变化 ,以及 BGC-82 3细胞经姜黄素处理后细胞内钙分布的变化。结果表明姜黄素可引起细胞内钙库的动员和钙离子的释放。提示
To study the possible mechanisms of curcumin to induce apoptosis of tumor cells,determined the changes of calcium waves of BGC-823 and MCF-7 cells and the calcium distribution changes in BGC-823 cells which being treated with curcumin by fluo-4/AM fluorescent calcium ion probe.It was showed that curcumin could cause the mobilization of intracellular calcium warehouse and the release of calcium ions,which hints that the release of cellular endogenetic calcium ions may be one of the possible signal regular mechanisms of curcumin to induce apoptosis.
出处
《福建中医学院学报》
2004年第6期21-23,共3页
Journal of Fujian College of Traditional Chinese Medicine
