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动脉内留置导管药物持续灌注治疗股骨头缺血性坏死 被引量:12

The clinical research of catheter indwelling in artery for treatment of avascular necrosis of femoral head
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摘要 目的 :评价动脉内留置导管持续灌注药物治疗股骨头缺血性坏死 (AvNFH)的疗效及优点。方法 :对 3 7例AvNFH患者 (病变股骨头 43个 ) ,采用Seldinger′s穿刺术以 5FCobra导管超选择性置导管于旋股内、外侧动脉及闭孔动脉造影 ,灌注药物后 ,留置导管 ,连续 3d再灌注溶栓药物。结果 :所有患者症状均得到缓解 ,疼痛缓解率为 96.6% ,关节功能改善率为 93 .0 %。对 3 7例患者随访 12个月。关节功能改善的总优良率为 83 .7%。介入治疗AvNFH的总有效率为 97.7%。治疗后定期复查 ,X线平片、CT、MRI显示坏死骨质均有不同程度的吸收、修复及新骨形成。结论 :动脉内留置导管持续灌注药物治疗AvNFH的方法可靠 ,近期疗效显著 ,能缩短治疗周期 ,是一种新的有价值的介入治疗方法。 Objective:To study the efficacy of interventional therapy for avascular necrosis of femoral head.Methods:A 5F Cobra catheter was inserted superselectively in the supplying arteris of feucoral luad,and then vasodilative drugs were perfused via catheter.Thrombolytic drugs were perfused after the catheter was maintained for three days.Results:Seven days after interventional treatment,there were marked improvements in clinical symptoms,with relief or disappearance of pain (96.6%),improvement of function of hip joint (93.0%).A total restorable rate was 83.7% and a total effective rate of 97.7%.Re-examination with X-ray,CT,MRI after treatment showed absorption of necrotic bone in different degrees and repairment of new bone.Conclusion:A short-term follow-up indicates that it is useful and effective for catheter indwelling in artery with continuous infusion of thrombolytic and vasodilative medicine,traditional Chinese medicine and western medicine drugs to treat avascular necrosis of femoral head.This therapy can relieve pain,improve function of hip and delay the time of artificial joint replacement.It is a new and valuable interventional therapy method.
出处 《放射学实践》 2004年第11期840-843,共4页 Radiologic Practice
关键词 骨坏死 导管 留置 放射性 介入性 Necrosis avascular,femoral head Catheters,indwelling Radiology,interventional
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