摘要
目的探讨昆明地区小儿肺炎中非典型病原体感染情况。方法对符合肺炎诊断标准的772例患儿,应用荧光免疫法(IF)、微量凝集法(MAT)、颗粒凝集法进行非典型病原体肺炎支原体(MP)、肺炎衣原体(CPn)、嗜肺军团菌(Lp)、Q热立克次体IgM抗体检测,同时对59例非典型肺炎病原体阳性患儿进行双份血清抗体(IgM)检测,所有病例临床资料汇集分析。结果772例患儿中,非典型病原体感染212例,感染率27.5%,其中MP肺炎125例,阳性率16.2%(125/772);Lp感染100例,阳性率12.9%(100/772);肺炎衣原体13例,阳性率1.7%(13/772);Q热立克次体3例,阳性率0.4%(3/772)。双份血清检测59份,血清抗体4倍增高50例。所测病例3～6岁发病率较高占72.6%,无明显季节流行性。结论应高度重视小儿非典型肺炎病原体感染,双份血清检测对非典型病原体感染具有确诊意义。
Objective To Investigate the infection state of atypical pathogen by pneumonia of children in Kunming area.Methods Atibodies of serum samples to Mycoplasma pneumonia (MP),Legonella pneumophila (LP),Chlamydia pneumonia (Cpn),QF-Richettsia were detected by means of immunofluorscence (IF) and microagglutination test(MAT) in the 772 pneumonia children,and antibodies of the paired serum samples were detected in 59 chidren of atypical pathogen pneumonia.Result Atypical pathogen were found in 212 out of 772 children,infection rate were 27.5%;In total of 212 children,125(16.2%) caseswere MP,100(12.9%) caseswere LP,13(1.7%) cases were Cpn,3 (0.4%) cases were QF-Riehettsia.In total of 59 cases of the paired serum,the antibodies of serum sample of convalescent period increasing four times in 50 cases.It showed that the infection rate were higher in 3～6 years old and have no the seasonal papular.Conclusion Should value pneumonia of atypical pathogen in children,the paired serum samples were detected have important diagnostic significance.
出处
《医学研究通讯》
2004年第10期14-16,共3页
Bulletin of Medical Research
基金
昆明市科技局2003年计划项目(昆科技字03S40120)
