摘要
肿瘤坏死因子 α(TNF α)是一种多效的细胞因子 ,脑缺血后TNF α水平增高。TNF α能作用于多种细胞 ,通过多种途径加重缺血后脑损伤。中和TNF α治疗能缩小脑梗死面积、减轻临床症状和体征。TNF α与缺血性卒中的研究具有重要的临床意义。
Tumor necrosis factor-α (TNF-α) is a pleiotropic cytokine. The level of TNF-α will increase after ischemic stroke. TNF-α can have effect on many cell types and aggravate the brain damage after ischemic stroke through various approaches. The treatment of neutralizing TNF-α can not only reduce the infarct volume, but also alleviate clinical symptoms and signs. The research on TNF-α and ischemic stroke has important clinical significance.
出处
《国外医学（脑血管疾病分册）》
2004年第8期597-600,共4页
Foreign Medical Sciences Cerebrovascular Diseases
