摘要
研究了采用反相高效液相色谱测定苯扎贝特含量的方法 ,以磷酸盐缓冲液 (0 0 1mol/L的磷酸二氢钾用磷酸调节pH至 3 8) 甲醇 (4∶6 )为流动相 ,采用HypersilC18柱 (5 μm ,4 6mm× 15 0mm) ,检测波长为 2 30nm ,苯扎贝特在 0 0 114～0 114mg/mL范围内线性相关 ,回归方程为 :A =1 0 5× 10 4c(mg/mL) +2 70× 10 2 ,r =0 9997,此法简便、快速。
A HPLC method was established for the determination of benzafibrate.Hypersil C_(18) was used as the stationary phase and 0.01 mol/L KH_2PO_4-CH_3OH as the mobile phase.The method was simple,rapid and reliable.It was applied not only in determination of its content,but also in determination of the related substances.
出处
《化学试剂》
CAS
CSCD
北大核心
2004年第5期285-286,共2页
Chemical Reagents
