摘要
从α-萘乙酸出发,合成酰基异硫氰酸酯,然后与2-氨基-5-芳基-1,3,4-二唑反应合成了8个新的酰基硫脲类化合物 a～ h。所有化合物的结构均经元素分析、红外光谱、核磁共振氢谱和质谱确认。同时对6种病原菌进行了生物活性测试,结果发现,在50mg/L下,所有目标化合物对黄瓜灰霉病菌Botrytiscinereapers的抑制效果较好,除 a外,其他化合物抑制率都达到80%以上。
A series of novel N-(5-aryl-1,3,4-oxadiazol-2-yl)-N′-α-naphthylacetylthioureas were synthesized from 2-amino-5-aryl-1,3,4-oxadiazoles. Their structures had been confirmed by IR, MS,()~1H NMR and elemental analysis. The results of biological test showed that most of these (compounds) had good fungicidal activity. The fungicidal activity to Botrytis cinereapers, could mostly reach 80%.
出处
《农药学学报》
CAS
CSCD
2004年第3期71-73,共3页
Chinese Journal of Pesticide Science
基金
湖北省自然科学基金资助项目(99J059).
关键词
1
3
4-嗯二唑
酰基硫脲
合成
杀菌活性
2-amino-5-aryl-1,3,4-thiadiazoles
acetylthiourea
synthesis
fungicidal activity
