摘要
目的 研究综合性干预措施对居民骨密度值 (BMD)及骨质疏松 (OP)患病率的影响 ,为OP的防治提供科学依据。方法 用整群随机抽样方法从上海市卢湾区 30～ 86岁健康人群中抽取5 98例为研究对象 ,将他们随机分为干预组和未干预组。要求干预组居民平时适当运动、合理营养 ,多食含钙、含VitD较高的食物等 ,干预时间为 3年 (2 0 0 0年 3月～ 2 0 0 3年 3月 )。两组居民均采用美国Lunar公司生产的双能X线骨密度仪测试L2 4和髋部的BMD ,然后进行统计、比较与分析。 结果干预组和未干预组骨量峰值 (PBM)均出现在 30～ 39岁 ,前者PBM值显著高于后者 (P <0 0 5 ) ;干预组所有部位BMD值均高于未干预组 (P <0 0 5 ) ,原发性OP患病率干预组显著低于未干预组 (P <0 0 5 )。结论 综合性的干预措施和加强健康教育、合理营养和运动 ,可提高青春期居民的骨峰值 ,对4 0岁以上中老年人可以减少其骨量丢失和减缓原发性OP的发生。
Objective To investigate the effects of bone mineral density (BMD) and the incidence of osteoporosis (OP) after three year intervention in Shanghai people, thereby providing scientific basis for prevention of OP. Methods The study population consisted of 598 healthy people aged 30-86 years. They were randomly divided into intervention group and no intervention group. The people of intervention group were required to strengthen physical exercise, take rationaldiet, and eat foods containing rich calcium and VitD. The intervention lasted for three years (March 2000 to March 2003). BMD of L 2-4 and upper femur were measured by DEXA, and were compared and statistically analyzed. Results Peak bone mass (PBM) appeared at 30-39 years of age in both groups. The PBM in intervention group was higher than that in no intervention group(P<0.05). The incidence of OP in intervention group was lower than that in no intervention group. Conclusions Health education, rational diet and physical exercise elevate PBM in adolescents, and reduce over bone loss and slow down the progress of primary OP in middle-aged and old people 40 years.
出处
《中国骨质疏松杂志》
CAS
CSCD
2004年第3期296-298,共3页
Chinese Journal of Osteoporosis
基金
上海市科学发展基金项目 ( 0 0 15 )
