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大鼠脊髓压迫后神经功能特征监护参数的变化 被引量:2

Changes of characteristic parameters in monitoring neurofunction following rat spinal cord compression injuries
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摘要 目的 研究体感诱发电位时频域特征参数用于监护脊髓压迫损伤的敏感性和有效性。 方法 记录大鼠脊髓压迫前后的脊髓体感诱发电位 ,分别用时频分析的短时傅里叶变换(STFT)和连续小波变换 (CWT)获得时频域的峰时间、峰频率和峰功率三个新的特征参数。 结果 脊髓压迫后 ,诱发电位在时域幅值平均降低 35 .5 % ,潜伏期平均延长 8.6 % (P <0 .0 5 )。而时频域的STFT和CWT获得的峰时间在压迫后分别延长 2 4 .9%和 36 .0 % (P <0 .0 1)、峰频率增加36 .4 %和 5 3.9% (P <0 .0 1)、峰功率分别降低 4 1.3%和 32 .5 % (P <0 .0 1)。 结论 时频域特征参数比时域参数能够更敏感和有效地反映术中脊髓压迫损伤。 Objective To evaluate sensitivity and effectiveness of characteristic parameters of time-frequency domain at cortical somatosensory evoked potential (CSEP)in monitoring spinal compression injuries. Methods CSEP was recorded in rats before and after spinal compression injuries. Three new characteristic parameters including peak-time, peak-frequency and peak-power were obtained by short time Fourier transform (STFT) and continuous wavelet transform (CWT) of time-frequency analysis. Results After spinal compression injuries, CSEP amplitude was decreased for 35.5% and latency delayed for 8.6% (P<0.05). Posterior to compression, in time-frequency domain, peak-time by STFT was delayed for 24.9% and that by CWT for 36.0%, respectively (P<0.01); peak-frequency increased for 36.4% and 53.9%, respectively (P<0.01); and peak-power decreased for 41.3% and 32.5%, respectively (P<0.01). Conclusions Characteristic parameters of peak-time, peak-frequency and peak-power in time-frequency domain are more effective and sensitive in monitoring intraoperative spinal cord compression than those of latency and amplitude in time domain.
出处 《中华创伤杂志》 CAS CSCD 北大核心 2004年第9期556-558,共3页 Chinese Journal of Trauma
关键词 大鼠 脊髓压迫 神经功能 监护参数 诱发电位 脊髓损伤 Spinal cord injuries Evoked potentials, somatosensory Fourier transform infrared spectroscopy Time-frequency analysis
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参考文献8

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