摘要
目的:探讨肺通口服液对严重急性呼吸综合征(severeacuterespiratorysyndrome,SARS)康复者的治疗作用。方法:将28例确诊的SARS康复者随机分为对照组和治疗组。首诊行常规肺功能及影像学检测后,治疗组给予肺通口服液治疗,对照组不予任何治疗。3个月后复诊,再次行肺功能及影像学检测。结果:复诊时肺功能检测的指标与首诊时比较:对照组:肺活量犤(3.23±0.48)L比(2.81±0.51)L,差异有显著性意义(t=5.39,P<0.05)犦;一秒用力肺活量(forcedexpiratoryvolume1,FEV1)犤(2.43±0.48)L比(2.17±0.51)L,差异有显著性意义(t=4.85,P<0.05)犦;肺一氧化碳弥散量(diffusingcapacityofthelungforcarbonmonoxide,DLCO)犤(17.01±2.20)mL/(min·mmHg)比(14.11±2.25)mL/(min·mmHg),差异有显著性意义(t=4.82,P<0.05)犦;治疗组:肺活量犤(3.55±0.84)L比(3.02±0.63)L,差异有显著性意义(t=3.69,P<0.05)犦;FEV1犤(2.90±0.66)L比(2.48±0.48)L,差异有显著性意义(t=3.97,P<0.05)犦;DLCO犤(17.23±4.16)mL/(min·mmHg)比(14.31±2.42)mL/(min·mmHg),差异有显著性意义(t=3.04,P<0.05)犦。治疗组肺功能检测的指标与对照组比较,差异均无显著性意义(t=0.18～2.17,P>0.05)。结论:SARS所致的肺损害在康复期内具有一定的自我修复能力,同?
AIM:To explore the therapeutic effect of feitong oral solution on recovered patients with severe acute respiratory syndrome(SARS). METHODS:Twenty eight patients, who were diagnosed to have SARS,were randomly divided into control group and treatment group.After initial examination of lung function and chest image, the patients in the treatment group were treated with feitong oral solution,whereas those in the control group received no treatment. All the patients were re examined for lung function and chest image after 3 months. RESULTS:In comparison of lung function results of re examination with initials,in the control group: vital capacities(VC) were(3.23±0.48) L and(2.81±0.51) L (t=5.39,P< 0.05), forced expiratory volumes in the first second (FEV1) were (2.43±0.48) L and(2.17±0.51) L(t=4.85,P< 0.05),diffusing capacities of the lung for carbon monoxide(DLCO) were (17.01±2.20) mL/mm Hg per minute and(14.11±2.25) mL/mm Hg per minute(t=4.82,P< 0.05);In the treatment group: VC were (3.55±0.84) L and (3.02±0.63) L (t=3.69,P< 0.05),FEV1 were (2.90±0.66) L and (2.48±0.48) L (t=3.97, P< 0.05),DLCO were [(17.23±4.16) mL/mm Hg per minute and (14.31±2.42) mL/mm Hg per minute](t=3.04,P< 0.05). There were in significant differences in the indexes of lung function between the treatment group and control group(t=0.18 to 2.17, P >0.05). CONCLUSION:Lung damage caused by SARS has certain self rehabilitative ability,and the results indicate that feitong oral solution might have no clinical therapeutic effect during the rehabilitation of SARS patients.
出处
《中国临床康复》
CSCD
2004年第27期5884-5885,共2页
Chinese Journal of Clinical Rehabilitation
基金
国家高技术研究发展计划课题资助项目(2003AA208107)~~
