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首次脑卒中后血管性痴呆的发生与病变部位的关系 被引量:10

Correlation between the occurrence of vascular dementia and the stroke-position after first attack of stroke
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摘要 目的:探讨首次脑卒中病变部位与血管性痴呆(vasculardementia,VD)发生的相关性。方法:用简易智能量表(MMSE)对首次脑卒中患者(脑梗死患者269例,脑出血患者94例)考核,并于脑卒中后3个月随访,用头颅CT或MRI确定病变部位。结果:患者脑卒中后3个月VD的发生率脑梗死组为17.8%(48/269);脑出血组为19.2%(18/94),两组差异无显著性意义(χ2=0.082,P>0.05)。脑卒中后痴呆及非痴呆患者病变部位经Logistic分析提示:脑梗死患者丘脑梗死对痴呆的影响程度最大,其次依次为梗死伴皮层下白质脑病、颞叶及多发性腔隙性脑梗死。脑出血患者丘脑出血对痴呆的影响程度最大,其次为颞叶出血。结论:血管性痴呆在首次脑卒中患者中常见,脑卒中后VD的发生与否与病变部位密切相关。 AIM:To explore the relationship between the occurrence of vascular dementia(VD) and the stroke-position in patients with first stroke. METHODS:All patients induding 269 patients with cerebral infarction(CI) and 94 patients with cerebral hemorrhage(CH) were examined with the mini-mental state examination(MMSE) at admission,and they were followed up for 3 months after stroke.The stroke-positions were diagnosed by using cranial CT or MRI. RESULTS:Three months after stroke,there were no significant differences in the occurrence rates of VD between the CI group(17.8%,48/269) and CH group(19.2%,18/94) (χ2=0.082,P >0.05).The results of Logistic analysis of stroke-position in patients with or without dementia after stroke indicated that,for the patients with CI,infarction in thalamencephalon was the most important influencing factor for VD,and followed by infarction accompanied with the subcortical leukoencephalopathy,temporal lobe,multiple lacunar infarction in order;and for the CI patients,thalamic hemorrhage had the most important effect on VD,followed by the hemorrhage of temporal lobe.CONCLUSION:VD commonly occurs in the patients with first stroke,and the occurrence of post-stroke.VD is closely related with the stroke position.
出处 《中国临床康复》 CSCD 2004年第25期5238-5239,共2页 Chinese Journal of Clinical Rehabilitation
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