摘要
目的 :通过动物实验 ,探讨儿童股骨头缺血性坏死与髋关节一过性滑膜炎之间的相互关系。方法 :4 0只 2～ 3月大小的幼狗 ,随机分为 4组 ,分别在髋关节内注入 2‰的去甲肾上腺素 (NA) ,在不同时间用99m锝———亚甲基二磷酸盐 ( 99mTC MDP)三相骨显像 ,观察股骨头局部循环血流变化 ,同时测定关节内压变化及行病理组织学检查 ,观察整个髋关节的病理变化及发展过程。结果 :NA不仅引起股骨头局部血流量的变化 ,也导致髋关节滑膜一过性炎症反应 ,但未引起股骨头缺血性坏死。结论 :NA可能在髋关节一过性滑膜炎发病机理中起重要的作用 ,髋关节一过性滑膜炎可能是一单独疾病 。
Objective:To study the causal correlation between transient synovitis of hip and Perthes’ disease. Methods: Forty 2-3 months old dogs were divided into 4 groups randomly and subjected to injection of 0.2% NA into the hip joint. Three assessments have been used in the experiment: (1) 99m TC MDP triphasic imaging was used to observe the local blood supply of femoral head; (2) Intra articular pressure was determined; (3) Pathological changes were observed to understand the natural course of the disease process. Results: Noradrenaline could result in the changes of the local blood supply of femoral head and transient synovitis of hip. There was no any necrosis of femoral head observed. Conclusion: Noradrenaline may be play an important role in the pathogenesis of transient synovitis of hip and transient synovitis is probably a separate disease entity and not antecedent to Perthes’ disease.
出处
《中国康复》
2004年第4期204-205,208,共3页
Chinese Journal of Rehabilitation
