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原发性开角型青光眼正常眼压时共焦扫描激光多普勒视网膜血流图 被引量:1

Confocal laser scanning Doppler flowmetry in primary open-angle glaucoma with normal IOP
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摘要 目的 探讨中国人中原发性开角型青光眼患者眼压在正常范围时视乳头和视网膜的血流动力学。方法 应用共焦扫描激光多普勒视网膜血流图检测 82例原发性开角型青光眼 15 0眼眼压控制在 2 2mmHg以下时视乳头和视网膜血流。结果 视乳头平均血容量、血流速和红细胞移动速率分别是 10 4 3 5± 49 2 4,3 2 43 93± 15 89 72 ,8 3 8±3 0 7;筛板处平均血容量、血流速和红细胞移动速率分别是 7 2 8± 4 18,10 8 5 5± 80 5 1,0 3 9± 0 2 5。盘沿处平均血容量、血流速和红细胞移动速率分别是 2 0 2 1± 16 86,5 2 9 91± 5 2 0 74,1 68± 1 3 2 ;盘缘外视网膜平均血容量、血流速和红细胞移动速率分别是 13 5 6± 5 97,2 5 7 90± 13 8 11,0 92± 0 46;视网膜平均血容量、血流速和红细胞移动速率分别是 17 96±6 2 3 ,3 5 0 3 9± 179 82 ,1 2 3± 0 5 7;血管、筛板和视网膜的血容量、流速和红细胞移动速率和正常眼比较都有明显下降。结论 原发性开角型青光眼患者存在着血流动力学障碍。 ObjectiveTo discuss the hemodynamic crises in optic nerve and retina in primary open-angle glaucoma with IOP below 22 mmHg.MethodsThe perfusion of the optic nerve head and retina in 150 eyes of 82 primary open-angle glaucoma individuals with normal IOP was measured with confocal scanning laser Doppler retinal flowmetry.ResultsThe average volume,flow and velocity of the vessels were 104.35±49.24, 3 243.93± 1 589.72,8.38±3.07 in optic nerve head,7.28±4.18,108.55±80.51,0.39±0.25 in lamina cribrosa,20.21±16.86,529.91±520.74,1.68±1.32 in rim,13.56±5.97,257.90±138.11,0.92±0.46 in juxtapapillary retina and 17.96±6.23,350.39±179.82,1.23±0.57 in retina.The volume,flow and velocity in vessel,laminar cribrosa and retina were significantly reduced compared with the normal eyes.ConclusionPrimary open-angle glaucoma has hemodynamic crisis.
出处 《眼科研究》 CSCD 北大核心 2004年第4期399-402,共4页 Chinese Ophthalmic Research
基金 卫生部重点资助项目 (970 30 2 2 5)
关键词 原发性开角型青光眼 视网膜 视乳头 激光 多普勒血流图 primary open-angle glaucoma retina optic nerve head laser Doppler flowmetry
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  • 1Flammer J,Orgul S,Costa VP,et al.The impact of ocular blood flow in glaucoma [J].Prog Retin Eye Res,2002,21(4):359-393
  • 2Birinci H,Danaci M,Oge I,et al.Ocular blood flow in healthy and primary open-angle glaucomatous eyes[J].Ophthalmologica,2002,216(6):434-437
  • 3Embleton SJ,Hosking SL,Roff HEJ,et al.Effect of senescence on ocular blood flow in the retina,neuroretinal rim and lamina cribrosa,using scanning laser Doppler flowmetry[J].Eye,2002,16(2):156-162
  • 4Michelson G,Langhans MJ,Groh MJM.Perfusion of the juxtapapillary retina and neuroretinal rim in primary open-angle glaucoma[J].J Glaucoma,1996,5:91-98
  • 5Findl O,Rainer G,Dallinger S,et al.Assessment of optic disk blood flow in patients with open-angle glaucoma[J].Am J Ophthalmol,2000,130(5):589-596
  • 6Arend O,Remky A,Plange N,et al.Capillary density and retinal diameter measurements and their impact on altered retinal circulation in glaucoma:a digital fluorescein angiographic study[J].Br J Ophthalmol,2002,86(4):429-433
  • 7Kurokawa T,Katai N,Shibuki H,et al.BDNF diminishes caspase-2 but not c-Jun immunoreactivity of neurons in retinal ganglion cell layer after transient ischemia[J].Invest Ophthalmol Vis Sci,1999,40(12):3006-3011
  • 8Nicolela MT,Hnik P,Schulzer M,et al.Reproducibility of retinal and optic nerve head blood flow measurements with scanning laser Doppler flowmetry[J].J Glaucoma,1997,6:157-164
  • 9Kerr J,Nelson P,O'Brien C.A comparison of ocular blood flow in untreated primary open-angle glaucoma and ocular hypertension[J].Am J Ophthalmol,1998,126(1):42-51
  • 10Hafez AS,Bizzarro RL,Lesk MR.Evaluation of optic nerve head and peripapillary retinal blood flow in glaucoma patients,ocular hypertensives,and normal subjects[J].Am J Ophthalmol,2003,136(6):1022-1031

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  • 1李俊,临床眼科诊治进展,1996年,17页

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