摘要
目的 探讨中国人中原发性开角型青光眼患者眼压在正常范围时视乳头和视网膜的血流动力学。方法 应用共焦扫描激光多普勒视网膜血流图检测 82例原发性开角型青光眼 15 0眼眼压控制在 2 2mmHg以下时视乳头和视网膜血流。结果 视乳头平均血容量、血流速和红细胞移动速率分别是 10 4 3 5± 49 2 4,3 2 43 93± 15 89 72 ,8 3 8±3 0 7;筛板处平均血容量、血流速和红细胞移动速率分别是 7 2 8± 4 18,10 8 5 5± 80 5 1,0 3 9± 0 2 5。盘沿处平均血容量、血流速和红细胞移动速率分别是 2 0 2 1± 16 86,5 2 9 91± 5 2 0 74,1 68± 1 3 2 ;盘缘外视网膜平均血容量、血流速和红细胞移动速率分别是 13 5 6± 5 97,2 5 7 90± 13 8 11,0 92± 0 46;视网膜平均血容量、血流速和红细胞移动速率分别是 17 96±6 2 3 ,3 5 0 3 9± 179 82 ,1 2 3± 0 5 7;血管、筛板和视网膜的血容量、流速和红细胞移动速率和正常眼比较都有明显下降。结论 原发性开角型青光眼患者存在着血流动力学障碍。
ObjectiveTo discuss the hemodynamic crises in optic nerve and retina in primary open-angle glaucoma with IOP below 22 mmHg.MethodsThe perfusion of the optic nerve head and retina in 150 eyes of 82 primary open-angle glaucoma individuals with normal IOP was measured with confocal scanning laser Doppler retinal flowmetry.ResultsThe average volume,flow and velocity of the vessels were 104.35±49.24, 3 243.93± 1 589.72,8.38±3.07 in optic nerve head,7.28±4.18,108.55±80.51,0.39±0.25 in lamina cribrosa,20.21±16.86,529.91±520.74,1.68±1.32 in rim,13.56±5.97,257.90±138.11,0.92±0.46 in juxtapapillary retina and 17.96±6.23,350.39±179.82,1.23±0.57 in retina.The volume,flow and velocity in vessel,laminar cribrosa and retina were significantly reduced compared with the normal eyes.ConclusionPrimary open-angle glaucoma has hemodynamic crisis.
出处
《眼科研究》
CSCD
北大核心
2004年第4期399-402,共4页
Chinese Ophthalmic Research
基金
卫生部重点资助项目 (970 30 2 2 5)