摘要
目的 :探讨葡萄糖酸钙和乳酸钙在大鼠体内的吸收和利用。方法 :断乳雄性 Wistar大鼠 5 0只 ,随机分成 5组 ,分别用碳酸钙、奶粉钙、葡萄糖酸钙和乳酸钙配制的饲料及基础低钙饲料喂养动物 2 8d,并分别在第2 0天和第 2 5天进行 3d食物效价实验及 4 d钙代谢实验。结果 :葡萄糖酸钙组大鼠体重增长率为 92 .1% ,钙吸收率及储留率分别为 6 8.2 %和 85 .1% ,股骨指数为 4 .96 ,股骨钙存留率为 4 .6 % ,各项指标均低于奶粉钙组 ,高于碳酸钙组 (P<0 .0 5或 P<0 .0 1)。乳酸钙组大鼠体重增长率为 75 .1% ,钙吸收率及储留率分别为 6 5 .5 %和82 .0 % ,股骨指数为 4 .88,股骨钙储留率为 4 .1% ,优于碳酸钙组 (P<0 .0 5或 P<0 .0 1) ,乳酸钙组除体重增长率低于葡萄糖酸钙组外 ,其他指标与葡萄糖酸钙组比较差异无显著性。结论 :葡萄糖酸钙和乳酸钙均可以作为机体的良好钙源 ,应用于食品添加剂和药物。
Objective To study the absorpion and utilization of calcium gluconate and calcium lactate in rats in vivo. Methods Weaning male Wistar rats were randomly divided into 5 groups and fed on CaCO 3, skimmed milk powder, calcium gluconate, calcium lactate, and basic low calcium meal in semi-purified diets, respectively, for 4 weeks. Meanwhile,the experiments of 3 days′ feed efficiency and 4 days′ calcium metabolism were carried out on the 20th and 25th day, respectively. Results In calcium-gluconate group, the incremental rate of body weight,the absorption and retention rate of calcium,the femur index, and retention rate of calcium in femur were 92.1%,68.2%,85.1%,4.96, and 4.6%, respectively, all indexes were lower than those in milk-powder group and higher than those in CaCO 3 group (P<0.05 or P<0.01). The items mentioned above in calcium-lactate group were 75.1%,65.5%,82.0%,4.88 and 4.1%, respectively,also higher than those in CaCO 3 group (P<0.05 or P<0.01),no differences were found between calcium-gluconate group and calcium-lactate group except that the incremental rate of body weight in calcium-lactate group was lower than that in calcium-gluconate group.Conclusion Both calcium gluconate and calcium lactate can be served as the good sources for dietary calcium supplement.
出处
《吉林大学学报（医学版）》
CAS
CSCD
北大核心
2004年第4期546-548,共3页
Journal of Jilin University：Medicine Edition
基金
吉林省科技厅科学技术发展计划项目资助课题 (2 0 0 30 5 38- 3)
