摘要
目的系统评价超声乳化白内障吸除术(Phaco)和囊外白内障摘除术(ECCE)对患者视力的影响。方法检索:Medline数据库和中国生物医学文献数据库,对9篇有关:Phaco和ECCE临床疗效的随机对照临床试验文献进行Meta分析。以危险差判定Phaco(Phaco组)和ECCE(ECCE组)的治疗效果,并按照随机效应模型计算合并危险差。结果9篇文献共计白内障患者1192例。术后近期(术后时间<1周)和远期(术后时间>3个月)Phaco组与ECCE组视力≥0.5者的合并危险差分别为24％(95％可信区间为:10％-37％)和20％(95％可信区间为14％-25％),差异均有非常显著意义(P<0.001)。Phaco组和ECCE组手术并发症的发生率分别为36.8％和62.1％,差异有非常显著意义(P<0.01)。结论Phaco术后患者视力恢复快、好且稳定,手术并发症少;Phaco是一种疗效优于ECCE的复明手术。(中华眼科杂志,2004,40:474-477)
Objective To examine the efficacy of phacoemulsification (Phaco) versus extracapsular extraction (ECCE) on visual acuity. Methods 9 cases related with Phaco and ECCE were retrieved from PubMED and Chinese biomedical data base . The combinability of the studies was assessed in terms of clinical and statistical criteria. Treatment effect was measured as risk difference between phacoemulsification and extracapsular extraction. Pooled estimates were analyzed with computer according to a random-effects model. Results A total of 1192 patients were included in 9 trials. The pooled risk differences of visual acuity 0. 5 or better after surgery one week or 3 month were 24% (95% CI is 10% -37% ) , 20% (95% CI is 14%-25%) respectively. The complications extracapsular extraction rates ( 36. 8% ) of phacoemulsification was lower than extracapsular extraction ( 62. 1 % ). Conclusions Phacoemulsification is a safer and reliable surgery for restoration of visual acuity in patients with cataract, and is superior to extracapsular cataract extraction. (Chin J Ophthalmol,2004,40:474-477)
出处
《中华眼科杂志》
CAS
CSCD
北大核心
2004年第7期474-477,共4页
Chinese Journal of Ophthalmology
