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尿酸与多发性硬化 被引量:6

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摘要 近年来有关研究发现,多发性硬化病人的血清尿酸水平显著低于对照,且可能与疾病的活动性、病程、神经伤残程度及性别有关。尿酸被成功地用于治疗多发性硬化的动物模型,多发性硬化病人口服尿酸前体肌苷可以使临床症状改善,提示对尿酸与多发性硬化的关系研究,有望为进一步探索多发性硬化发病机理及更合理的治疗方案找到新的突破点。
出处 《国外医学(神经病学.神经外科学分册)》 2004年第3期258-260,共3页 Foreign Medical Sciences(Section On Neurology & Neurosurgery)
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同被引文献21

  • 1赵红如,董万利,方琪,倪建强,蒋建华.多发性硬化患者血清尿酸水平的变化及意义[J].中国临床神经科学,2004,12(3):234-235. 被引量:6
  • 2田林郁,周东.尿酸在中枢神经系统脱髓鞘疾病诊断、治疗和预防中的意义(综述)[J].中国神经免疫学和神经病学杂志,2004,11(5):283-285. 被引量:4
  • 3李海峰,梁兵,丛志强.多发性硬化和尿酸[J].中国现代神经疾病杂志,2005,5(1):51-53. 被引量:8
  • 4赵红如,董万利,方琪,倪建强,蒋建华.多发性硬化患者血清尿酸水平的变化及意义[J].中国全科医学,2006,9(6):496-497. 被引量:2
  • 5魏岗之.脱髓鞘性疾病的CT和MRI诊断.神经系统脱髓鞘性疾病,2002,16:10-10.
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  • 10Spitis SV,Scott GS,Kean RB,et al,Protection of myelin basic protein immunized mice from free radical mediated inflammatory cell invasion of the central nervous system by the natural peroxynitrite scavenger uric acid.Neurosci lett,2002,292(2):137-141.

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