期刊文献+

连续性肾替代治疗中透析液再循环的临床研究

Dialysate recycling in continuous renal replacement therapy
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摘要 目的 研究透析液再循环在连续性肾替代治疗 (CRRT)中的可行性。方法 将我院行连续性高通量透析 (CHFD)的 12 0例肾功能衰竭患者随机分成两组 ,其中 5 8例 2 0 0例次行透析液再循环 (A组 ) ,6 2例 2 5 0例次 (B组 )行传统CHFD即透析液不循环 ,观察比较疗效及不良反应发生情况。结果 A组透析后较透析前血尿素氮 (BUN)、肌酐 (Cr)平均下降分别为 (4 5 .2 3± 7.91) %和 (5 7.14± 10 .39) % ,高钾血症、酸中毒均能纠正 ,与B组相比差异无统计学意义 (P >0 .0 5 ) ;A组无 1例患者出现寒战、发热等致热源反应。结论 透析液再循环安全有效 ,透析液用量显著减少 。 Objective To evaluate the possibility of dialysate recycling in continuous renal replacement therapy(CRRT). Methods One hundred and twenty patients with kidney failure,who underwent continuous high flux dialysis(CHFD),were enrolled in this study.Fifty-eight patients performed dialysate recycling in 200 times of CHFD(group A),while sixty-two patients used fresh dialysate in 250 times of CHFD(group B).Effect and side effect of two groups were investigated and compared. Results In group A,serum urea nitrogen and creatinine were decreased by ( 45.23± 7.91)% and ( 57.14± 10.39)%, accompanied by well redressing of hyperkalemia and acidosis after CHFD.This effect had no significant difference with group B(P> 0.05).There was no pyretogenesis in group A. Conclusion Dialysate recycling in CRRT is effective, safe and economical.
出处 《临床荟萃》 CAS 北大核心 2004年第12期682-684,共3页 Clinical Focus
关键词 肾功能衰竭 肾替代疗法 透析液 设备安全性 kidney failure renal replacement therapy dialysis solutions equipment safety
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参考文献4

  • 1RONCO C, BRENDOLAN A,BELLOMO R.Online efficiency and efficacy in relation to solute size[J].Kidney Int,1999,72(suppl 11):s3-7.
  • 2SCHETZ M R.Classical and alternative indications for continuous renal replacement therapy[J].Kidney Int, 1998,53(suppl 66):s129-132.
  • 3RONCO C,BRENDOLAN A,BELLOMO R.Current technology for continuous renal replacement therapies[A].In:Ronco C,Bellomo R,ed.Critical care nephrology[M].Netherlands:Kluwer Academia Publishers,1998.1269-1308.
  • 4王笑云.急性肾衰竭现代诊疗[M].南京:江苏科学技术出版社,1998.386-399.

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