摘要
目的 :观察硝普钠 (SNP)治疗慢性肾衰竭 (尿毒症期 )合并左心衰的疗效。方法 :将 4 1例慢性肾衰竭 (尿毒症期 )并左心衰、心功能IV级的住院患者随机分为两组 :治疗组 2 2例 ,在常规治疗包括强心剂、口服血管转换酶受体拮抗剂、β受体阻滞剂的基础上静脉持续点滴SNP2 0～ 80 μg/min ,观察4 8h ;对照组 19例 ,常规治疗同治疗组 ,静脉持续点滴硝酸甘油 (NTG) 5～ 15 μg/min ,观察 4 8h。 结果 :治疗组显效率 81.82 % ,总有效率 95 .4 5 % ;对照组显效率 5 2 .6 5 % ,总有效率 6 8.4 2 %。结论 :治疗组心功能改善情况明显优于对照组 ,且治疗组在呼吸、心率。
Objective: To observe the curative effect in treatment of chronic renal failure (CRF) amalgamate left heart failure (LHF) with Sodium Nitroprusside for Injection (SNP) . Method: We selected 41 confirmed cases of chronic renal failure.The subjects were randomly divided into 2groups : In the trial group there were 22 cases who were treated with SNP iv drip persistance (20～80μg/min) and were observed 48 hours. In the controlled group there were 19 cases who were treated with Nitroglycerin Injection (NTG) iv drip persistance ( 5～15μg/min) and were observed 48 hours. That two groups were on the bases of routine treatment (including Cedilanid ,Aprovel and Metoprolol Tartrate Tablets). Result: In the treating group, the apparent rate was 81.82%, the effective rate was 95.45%. In the controlled group, the apparent rate was 52.63%, the effective rate was 68.42%. Conclusion: The curative effect of SNP for chronic renal failure amalgamate left heart failure was better than NTG in heart function and breath and heart rate and blood pressure. These results suggest that SNP is aneffective and safe medicine in the treatment of chronic renal failure amalgamate left heart failure.
出处
《河北医学》
CAS
2004年第8期723-725,共3页
Hebei Medicine
关键词
硝普钠
硝酸甘油
慢性肾衰竭(尿毒症期)
左心衰
Sodium nitroprusside for injection (SNP)
Nitroglycerin injection
Chronic renal failure (uraemia period)
Left heart failure
