摘要
本文将80例无高血压、无明显心血管疾患病人分四组不同方法全麻诱导,进行气管内插管,比较心血管副反应。观察到硫喷妥钠+琥珀胆碱或安定、硫喷妥钠+琥珀胆碱诱导下插管,均可使动脉血压及心率明显增高(P<0.001),收缩压心率乘积超过心肌缺血阈值(RPP>12000、HR>90)者有二组共达60％,超过心绞痛阈值者(RPP>22000)共达10％,插管后呛咳病例也多。芬太尼6μg/kg+硫喷妥钠5mg/kg+琥珀胆碱或用安定0.2～0.4mg/kg代替硫喷妥钠的二组,上述反应明显减轻,插管后出现吞咽动作为主,呛咳者少,较适用于高血压、心血管疾患、颅内高压病人。由于尚有37.59％病人收缩压心率乘积超过心肌缺血阈值,故尚非理想的诱导方法。对短时间的手术及有呼吸系统疾患的病人尚需慎用。
Eighty patients with non-hypertension and no significant cardiovascular disease were divided four groups to observe the cardiovascular responses provoked by intubation during various intravenous inductions. Observations showed that patients inductioned with group 1 or group 2,the parameters of BP and HR were all significantly increased(P<0.001) after intubation. At the same time, 60% patients of RPP were more than 12,000 and HR were faster than 90. Among them 10 % cases of RPP wero more than 22,000. patients administered with group 3or group 4 , circulatory responses were obviously diminished. Results indicated that the use of Fentanyl as a main agent in induction may be consider as a comparatively suitable method for the patient with hypertension, cardiovascular disease or intracranial hypertension.
出处
《临床麻醉学杂志》
CAS
CSCD
北大核心
1989年第4期187-189,共3页
Journal of Clinical Anesthesiology
