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糖尿病大鼠微循环与坐骨神经细胞凋亡的相关性及中药复方的干预 被引量:3

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摘要 目的探究糖尿病(DM)大鼠微循环与坐骨神经细胞凋亡的相关性及益气活血通络中药的干预作用。方法采用链脲佐菌素复制DM大鼠模型,随机分为模型组、中药组、弥可保组,并设正常对照组。8 w后,检测体重、血糖及血液流变学、坐骨神经细胞凋亡情况。结果 DM大鼠体重降低,血糖升高,血液流变性改变、坐骨神经细胞发生凋亡,中药组与DM模型组及弥可保组比较均有显著差异。结论 DM大鼠微循环与坐骨神经细胞凋亡具有相关性,益气活血通络中药对二者具有改善作用,从而防治DM周围神经病变。
机构地区 长春中医药大学
出处 《中国老年学杂志》 CAS CSCD 北大核心 2014年第2期407-408,共2页 Chinese Journal of Gerontology
基金 吉林省科技厅项目(No.20120932) 吉林省教育厅项目(No.2013-77)
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