摘要
目的：探讨人群代谢异常与心电图异常的关系。方法选取卫生部疾病控制项目“全国高血压规范化管理”和卫生部行业基金项目“心血管病危险因素监测和高血压规范化管理”中宁夏分中心的基线资料2524例进行分析。调查内容包括问卷调查、体格检查、血压测量、实验室检查、心电图检查。结果心电图异常的检出率为15.2％，其中男10.2％，女19.7％，女性心电图异常检出率超过男性（ P＜0.001）。代谢异常的数量越多，心电图异常的检出率越高（ P＜0.05）。不同代谢异常数目下，代谢异常的组成存在差别，但统计学无显著差异。 Logistic回归分析统计结果显示4种代谢异常的风险最大〔OR＝4.19，95％ CI（2.62～6.70）〕，一种代谢异常的人群，血糖异常对心电图异常的检出风险最大；两种代谢异常的人群，血压升高合并血脂异常对心电图异常的检出风险最大；3种代谢异常的人群，血压升高合并中心性肥胖与血脂异常对心电图异常的检出风险最大。结论随着代谢异常的数量增多，心电图异常的检出率增高。一种代谢异常的人群，应重点干预血糖异常；两种代谢异常的人群，应重点干预血压升高合并血脂异常；3种代谢异常的人群，应重点干预血压升高合并中心性肥胖与血脂异常。
Objective To explore the relationship between metabolic disorders and abnormal electrocardiogram .Methods The baseline data of 2 524 peoples who entered “Disease Control Project of the Ministry of Health-National High Blood Pressure standardized management” and“the Ministry of Health Industry Fund-cardiovascular disease risk factor surveillance and high blood pressure standardized management” in Ningxia were analyzed.Results The rate of ECG abnormality was 15.2%and the rate in the female was significantly high-er than it in the male (10.2%vs 19.7%, P<0.001).The rate of ECG abnormality increased with the number of metabolic abnormalities ( P<0.05 ).The composition of metabolic disorders was different under different numbers of metabolic disorders , though the differences were not significant (P>0.05).Logistic regression analysis showed that four metabolic abnormalities had greatest risk (OR=4.18,95%CI:2.61~6.69 ).Among the population with one metabolic disorder , hyperglycemia was the biggest risk factor of ECG abnormalities detected.In the peoples with two metabolic disorders , dyslipidemia combined with hypertension was the greatest risk factor of ECG abnormalities .Hy-pertension and central obesity and dyslipidemia were the greatest risk factor for ECG abnormalities in the peoples with three metabolic disor -ders.Conclusions The rate of the metabolic disorders is increased with the numbers of ECG abnormalities.The hyperglycemia should be intervened majorly in the peoples with one metabolic disorder , and hypertension and dyslipidemia should be majorly intervened in the peoples with two metabolic disorders , and hypertension and central obesity and dyslipidemia should be majorly to interventions for peoples with three metabolic disorders.
出处
《中国老年学杂志》
CAS
CSCD
北大核心
2014年第8期2211-2214,共4页
Chinese Journal of Gerontology
基金
卫生部疾病控制项目和卫生部行业基金项目(No.200902001)
关键词
代谢异常
心电图
心血管疾病
Metabolic disorder
ECG
Cardiovascular disease
