摘要
目的:观察扶正化瘀解毒法对晚期恶性肿瘤患者体质、疼痛、血液指标的改善情况。方法:对96例晚期恶性肿瘤患者属正气亏虚,瘀毒内结证型者口服扶正化瘀解毒汤,并观察治疗前后患者的中医症候积分、生活质量评分、疼痛评分及血常规的变化情况。结果:治疗前中医症候积分由20.4±2.5下降至19.6±1.7,有统计学意义。治疗后25%的患者疼痛完全解除,52.8%的患者疼痛减轻,总有效率为68.9%;80%的患者卡氏评分有所上升,治疗前后白细胞由3.57±0.79×109/L上升至4.59±0.87×109/L,血小板由123±47×109/L上升至146±49×109/L,P<0.01,差异有统计学意义。结论:扶正化瘀解毒汤用于晚期恶性肿瘤患者的姑息治疗,有减轻疼痛,改善患者恶病质体质,提高患者身体状况的作用,且无肝肾毒性等不良作用,可用于晚期恶性肿瘤的治疗。
Objective:To observe the effect on body constitution,pain and blood index in advanced malignant tumor using Fu zheng HuaYu JieDu method.Method:Fuzheng Huayu Jiedu decoction was administered to 96 patients with advanced malignant tumor of Zheng Qi Kui Xu and Yu Du Nei Jie symptoms.And the scores of TCM symptoms,quality of life,pain and blood routine examination were investigated before and after treatment.Result:The scores of TCM symptoms were decreased from 20.4±2.5 to 19.6±1.7 which had statistical significance.Pain was completely removed in 25% patients,and was relieved in 52.8% patients with the total effective rate of 68.9%;KPS of 80% patients was increased.After treatment,the white blood count was increased from 3.57±0.79×109﹒L-1 to 4.59±0.87×109﹒L-1,and platelet was increased from123±47×109﹒L-1 to 146±49×109﹒L-1(P < 0.01).The difference was statistically significant.Conclusion:The Fuzheng Huayu Jiedu method can relieve pain,improve body constitution,improve the status of the body function in advanced malignant tumor patients.No toxicity and adverse effect on the liver and kidney are found.The results show that the method can be used for the treatment of late malignant tumor.
出处
《中药与临床》
2012年第5期22-24,共3页
Pharmacy and Clinics of Chinese Materia Medica
关键词
扶正化瘀解毒法
恶性肿瘤
晚期肿瘤
Fu zheng HuaYu JieDu method
malignant tumor
advanced stage tumor
