摘要
目的探讨口腔癌放疗后复发癌挽救性手术应用带血管蒂肌皮瓣修复术后组织缺损的可行性。方法选择19例口腔癌患者,8例口腔癌放疗后复发癌行肿瘤扩大切除及颈淋巴清扫,同期应用带血管蒂肌皮瓣移植修复软组织缺损,并与11例术前未做放疗的口腔癌病例进行对照研究。结果两组肌皮瓣均未出现全部坏死情况,肌皮瓣成活率无显著性差异(P>0.05);放疗组伤口延期愈合,伤口愈合率有显著性差异(P<0.05)。1、3年生存率放疗组为62%和37%,对照组为81%和54%。结论带血管蒂肌皮瓣移植是修复口腔癌放疗后复发癌术后软组织缺损的有效方法。
Objective To explore the feasibility of the tissue defective repairing using myocutaneous flap with blood vessel in the operation of recurrent oral cancer patients after radiotherapy.Methods Eight recurrent oral cancer patients after radiotherapy were treated with extensive incision and neck lymph node scavenge.The tissue defectiveness were repaired using myocutaneous flap with blood vessel in the following operation.The outcomes were compared with 11 patients,who were not treated with radiotherapy.The data were analyzed with SAS 8.0 software.Enumeration data were evaluated with chi square test and the significant level was P<0.05.Results No myocutaneous flap tissue necrosis were appear in the two groups.No significant difference of survival rate for myocutaneous flap were found in the two groups(P>0.05).Delayed healing was found in the group of radiotherapy.Significant difference of wound healing rat were found in the two groups(P<0.05).1,3 years survival rate was 62% and 37% in the radiation group,54.7% and 81% in the placebo group.Conclusions The method of tissue defective repairing using myocutaneous flap with blood vessel in the operation of recurrent oral cancer patients after radiotherapy is an effective modality.
出处
《中华临床医师杂志（电子版）》
CAS
2012年第19期5810-5813,共4页
Chinese Journal of Clinicians(Electronic Edition)
关键词
口腔肿瘤
放射疗法
外科皮瓣
外科手术
Oral cancer
Radiotherapy
Myocutaneous flap
Surgical operation
