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5-氨基酮戊酸光动力疗法治疗面部鳞状细胞癌的临床观察 被引量:7

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摘要 皮肤鳞状细胞癌(squamous cell carcinoma,SCC)又称表皮样癌、棘细胞癌,系源于表皮或附属器角质形成细胞的皮肤恶性肿瘤,发病率仅次于基底细胞癌,约占非黑色素皮肤肿瘤的20%.SCC好发于中老年人头面部等暴露部位,近年来发病率呈持续上升的趋势[1].光动力疗法(photodynamic therapy,PDT)是一种联合应用光敏剂及相应光源,产生自由基和单态氧等强氧化剂引起局部病灶组织中肿瘤细胞受损、凋亡或坏死的非产热微创治疗方法,已逐渐应用于治疗消化道、呼吸道、耳鼻喉、眼科、泌尿系、皮肤等部位的肿瘤,不仅是一种缓解、姑息治疗的手段,而且对部分肿瘤,已可达到治愈目的.我们应用5-氨基酮戊酸光动力疗法(5-aminolevulinic acid photodynamic therapy,ALA-PDT)治疗16例面部鳞状细胞癌,取得了较满意的效果,现报道如下.
出处 《中华临床医师杂志(电子版)》 CAS 2012年第16期4931-4932,共2页 Chinese Journal of Clinicians(Electronic Edition)
基金 甘肃省自然科学基金(1107RJZA109)
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  • 2王宏伟,王秀丽,过明霞,虞叶风.5-氨基酮戊酸乳膏光动力疗法治疗皮肤癌前病变和皮肤原位癌[J].中华皮肤科杂志,2006,39(3):137-139. 被引量:49
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