Expression of insulin-like growth factor Ⅱ and its receptor in hepatocellular carcinogenesis 被引量：24

Expression of insulin-like growth factor Ⅱ and its receptor in hepatocellular carcinogenesis

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摘要 INTRODUCTIONInsulin-like growth factor Ⅱ(IGF-Ⅱ) is a mitogenic peptide of 74 kD and is mostly synthesized in fetal liver tissue .IGF-Ⅱ is believed to play an important role in fetal growth and development and is involved in cellular proliferation and differentiation[1-5]. Recently ,several researchers have reported increased expression of the IGF-Ⅱgene in human hepatocellular carcinoma (HCC) and adjacent non-cancerous liver tissues [6-10].

作者 Zi Rong Fan Dong Hua Yang Jun Cui Han Rong Qin Chun Chi Huang Department of Gastroenterology, Zhujiang Hospital. The First Military Medical University, Guangzhou 510282.Guangdong Province. China

出处《World Journal of Gastroenterology》 SCIE CAS CSCD 2001年第2期285-288,共4页 世界胃肠病学杂志（英文版）

基金 Project supported by the National Nature Science Foundation of China,No.39470774

关键词 liver neoplasms/pathology insulin-like growth factor Ⅱ/biosynthesis receptors somatomedin/biosynthesis RNA messenger/biosynthesis in situ hybridization hepatitis chronic/pathology liver neoplasms/pathology insulin-like growth factor H/biosynthesis receptors,somatomedin/biosynthesis RNA, messenger/biosynthesis in situ hybridization hepatitis,chronic/pathology

分类号 R735.7 [医药卫生—肿瘤]

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