摘要
目的:观察厄贝沙坦治疗非杓型高血压患者降压效果及其杓型血压昼夜节律恢复情况,并观察治疗后血浆醛固酮水平的影响。方法:对杓型和非杓型两组原发性高血压患者分别给予150-300 mg/d,观察降压效果及对血压昼夜节律的影响,并监测用药前后血浆醛固酮水平的变化。结果:所有高血压患者应用厄贝沙坦治疗前后收缩压及舒张压均有不同程度的下降,非杓型组夜间收缩压及舒张压的下降值与杓型相比有统计学差异,出现了明显的昼夜节律,血浆醛固酮水平出现了明显差异。结论:厄贝沙坦对非杓型高血压患者有良好的降压作用,并能恢复非杓型高血压患者的昼夜节律,向杓型血压变化。
Objective: To investigate the effect of blood pressure control and circadian variability of dipper blood pressure induced by irbesartan in patients with non-dipper essential hypertension and to observe levels of aldosterone.after treatment.Methods: The patients were divided into dipper and non-dipper groups.All patients were treated with irbesartan(150-300 mg/d).The variability of circadian blood pressure were observed,and the levels of plasma aldosterone were monitored before and after treatment Results: A...
出处
《华西医学》
CAS
2009年第12期3115-3117,共3页
West China Medical Journal
关键词
厄贝沙坦
高血压
非杓型
醛固酮
essential hypertension
non-dipper
aldosterone
