摘要
目的探讨孕中期孕妇凝血酶原时间(PT)、活化部分凝血活酶时间(APTT)、凝血酶时间(TT)、纤维蛋白原(FIB)、抗血酶Ⅲ(ATⅢ)、蛋白C(PC)、蛋白S(S)、纤维蛋白降解产物(FDP)和D二聚体(DD)检测的临床意义。方法PT、APTT、TT、Fib测定均为凝固法,所有指标均由SYSMEXCA-1500全自动血凝仪进行测定。结果对55例孕中期孕妇(实验组)与55例正常非妊娠妇女(对照组)的凝血功能进行比较分析。孕中期孕妇组PT、APTT、TT、Fib、ATⅢ、PC、PS、FDP和DD值与对照组比较差异有显著性(P<0.01)。结论在妊娠中期孕产妇凝血功能发生了显著变化,表现为妊娠相关的高凝血状态和存在血栓并发症风险,孕产妇需要监测凝血功能。
Objective To explore the clinical significance of prothrombin time(PT),activated partial thromboplastin time(APTT),thrombin time(TT),plasma fibrinogen(FIB),antithronbin Ⅲ(ATⅢ),protein C(PC),protein S(PS),fibrin degrad(FDP),and D-Dimer(DD) for pregnancy women in middle terms.Methods PT、APTT、TT、Fib were assayed using coagulation method,all the peremeters were finished by CA-1500 automated blood coagulation analyzer.Results We analyzed the difference of function of blood coagulation between 55 pregnancy women in middle terms(experiment group) and 55 normal women without pregnant(control group).There was extreme significant difference(P<0.01) between pregnancy women in middle terms and normal women without pregnancy on all the peremeters finished.Conclusion The normal pregancy women in middle terms have a much changes in coagulation system,showing a pregnancyrelated hypercoagulate state and existing risks of thrombotic complication.Observation of coagulation function for pregnancy women is necessary.
出处
《医学检验与临床》
2008年第2期49-50,共2页
Medical Laboratory Science and Clinics
关键词
孕妇
凝血酶原时间
活化部分凝血酶时间
凝血酶时间
纤维蛋白原
高凝状态
Pregnancy women
Prothrombin time(PT)
Activated partial thromboplastin time(APTT)
Thrombin time(TT)
Plasma fibrinogen(FIB)
Hypercoagulate state
