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脑分水岭梗死的临床特点及其发病机制研究 被引量:50

The Study of the Clinical Features and Pathogenesis of Cerebral Border-zone Infarction
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摘要 目的探讨脑分水岭梗死的临床特点及其发病机制。方法根据脑血管分布的影像学模板,回顾分析124例脑分水岭梗死患者的临床资料,确定并分析皮质分水岭梗死、皮质下型分水岭梗死和混合分水岭梗死3组患者的临床特征及病理生理机制。结果3组脑分水岭梗死患者的临床特征间差别无显著性意义(P>0.05);皮质分水岭梗死的发病率与皮质下型分水岭梗死间差别有显著性意义(P<0.001)。其中接受DSA检查的95例患者中,75.0%的皮质分水岭梗死有严重血管狭窄,60.7%皮质下型分水岭梗死有严重血管狭窄,9例混合分水岭梗死患者均有严重血管狭窄。结论分水岭梗死与脑动脉血管狭窄有密切的关系。 Objective To explore the clinical features and pathogenesis of cerebral border-zone infarction.Methods We reviewed 1023 consecutive patients with ischemic stroke.The patients with cortical border-zone infarction (CBI),inter- nal border-zone infarction (IBI) and combined broder-zone infarction were selected based on the neuroradiological template. The clinical features and pathogenesis were compared among three groups.Results We identified 124 (12.1%) patients. There was no difference in clinical characteristics among three groups (P>0.05).The incidence of internal border-zone in- farction was significantly higher than cortical border-zone infarction and combined border-zone infarction (9.0%:1.9%: 1.2% P<0.001).Among 95 patients who received cerebral vascular digital subtraction angiography (DSA),75% (9/12) patients with cortical border-zone infarction had serious vascular stenosis (stenosis>50%),60.7% (33/84) patients with internal border-zone infarction had serious vascular stenosis.9 patients with combined border-zone infarction had serious vas- cular stenosis.Conclusion The cerebral border-zone infarction is associated with serious vascular stenosis.
出处 《中国卒中杂志》 2006年第4期246-251,共6页 Chinese Journal of Stroke
关键词 分水岭梗死 临床特点 发病机制 全脑动脉血管造影 Cerebral border-zone infarction Clinical features Onset mechanisms Digital subtraction angiography
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