摘要
目的:总结正常软骨在改良脂肪抑制三维真实稳态自由进动序列上的表现,与传统序列对比研究软骨显像的图像质量,探讨经过改良以后的脂肪抑制三维真实稳态自由进动序列应用于软骨成像的可行性。方法:应用脂肪抑制三维快速小角度激发序列、三维双回波稳态序列、脂肪抑制快速自旋回波质子密度加权序列,以及经过改良以后的两个脂肪抑制三维真实稳态自由进动序列,对10名志愿者的膝关节进行扫描。测量各序列软骨及关节滑液的信号强度及背景噪声,计算各种方法所得图像的关节软骨的信噪比、关节软骨与滑液的对比噪声比及对比噪声比效率,比较各序列所得的信噪比、对比噪声比及对比噪声比效率之间有无统计学差异。结果:在改良的序列上软骨信号强度介于关节液与邻近骨质之间。6例信号均匀,4例软骨信号可见与脂肪抑制三维快速小角度激发序列相似的分层现象,各序列的信噪比、对比噪声比及对比噪声比效率差异具有显著性。采集次数为2次的脂肪抑制三维真实稳态自由进动序列的对比噪声比及对比噪声比效率优于其他序列。结论:经过改良后的真实稳态自由进动序列可以在保持关节软骨一定的信噪比的前提下在短时间内获得与关节滑液之间具有良好对比噪声比的图像。真实稳态自由进动序列可以用于关节软骨病变的诊断。
Objective:To explore the feasibility of improved fat-saturated three-dimensional true fast imaging with steady-state precession (FS-3D-TrueFISP) sequence for imaging hyaline cartilage of the knee.Methods:Single knee of 10 volunteers was scanned with two FS-3D-TrueFISP sequences after improved and conventional hyaline cartilage defects sequences.Measured the signal intensity of the hyaline cartilage of patellar facets,synovial fluid and background noise respectively.The signal to noise ratio (SNR) of hyaline cartilage,contrast to noise ratio (CNR) of hyaline cartilage to synovial fluid and CNR efficiency (CNReff) was calculated for each of the five sequences.Statistically significant differences in SNR,CNR and CNReff were determined.Results:On improved sequence hyaline cartilage showed moderate intensity,4 cases on FS-3D-TrueFISP showed three layers structure same as FS-3D-FLASH.The SNR,CNR and CNReff of the five sequences had statistically significant differences (P<0.05),the CNR and CNReff of FS-3D-TrueFISP,in which the number of acquisition is 2,was best.Conclusion:The improved TrueFISP sequence can image cartilage with excellent CNR in shorter scan time,this improved sequence can be used to image the hyaline cartilage in the knee.
出处
《CT理论与应用研究（中英文）》
2007年第2期80-85,共6页
Computerized Tomography Theory and Applications
基金
新世纪优秀人才支持计划(NCET)资助(985-2-070-113)。
关键词
磁共振成像
真实的稳态自由进动序列
图像质量
软骨
关节
magnetic resonance
true fast imaging with steady state precession imaging
image quality
cartilage
arthrosis
