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吡喹酮缓释剂防制牛血吸虫病试验 被引量:1

THE EXPERIMENT OF SLOW RELEASED PRAZIQUENTEL CONTROL TO CATTLE’S SCHISTOSOMA JAPONICUM
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摘要 应用吡喹酮缓释剂肌注 (每 m L含吡喹酮 3 5 7mg)与吡喹酮粉剂口服分别对我省大邑、旌阳、芦山等县查出的 84头血吸虫病病牛进行了治疗和观察。吡喹酮缓释剂组 3 4头 ,共分为 4组 , ~ 组 ,分别肌注 1 5 m L/头 (共9头 ) ,2 0 m L/头 (共 8头 ) ,2 5 m L/头 (共 9头 )及 0 .0 5 m L/kg体重。粉剂口服组 1 5头 ,水牛按 2 5 mg/kg体重 ,黄牛按3 0 mg/kg体重 ;对照组 3 5头 ,不用药物治疗。试验结果表明 :缓释剂组可在 In order to observe the effect of slow release praziquent (SRP) treating cattle's Schistosomiasis. We useing SRP (1mL contain 357 mg praziquentel) and praziquentel powder (PP) to treat 84 cattles infecteel with Schistosoma japonicum in Dayi, Jingyang and Lushan county. The cattles were divided into three groups, i.e. SRP, PP and untreated control group (35 cattles). Then, the cattles treated with SRP were divided into four groups: first group (9 cattles), each 15mL, Second group (8 cattles), each 20mL. Third group (9 cattles), each 25mL. Fourth group (8 cattles), each 0.05mL/kg·bw, were all intramuscularly injected. The PP group (15 cattles and buffalo) received the dose of drug: buffalo 25mg/kg·bw, cattle 30mg/kg·bw, were all oral adminstration. The result shows that SRP can effectively prevent cattle being reinfected with Schistosoma japonicum. Especially, those of SRP 2、3、4 group, preserve cattles for more than 3 months.
出处 《中国兽医寄生虫病》 2002年第3期6-8,共3页 Chinese Journal of Veterinary Parasitology
关键词 吡喹酮缓释剂 吡喹酮粉剂 牛血吸虫病 防治 slow released praziquentel praziquentel powder cattle Schistosoma japonicum control
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