摘要
为了深入了解最直接危害人体健康的微细可吸入颗粒物在人体上呼吸道中的运动情况,建立了一个包括口腔、咽、喉、气管和支气管的完整的人体上呼吸道三维几何模型,并且基于该模型对人体在稳态呼吸状况下,呼气、吸气时微细颗粒在人体上呼吸道中的运动进行了数值模拟。气流场采用RNGκ-ε湍流模型进行计算,在拉格朗日框架下追踪颗粒运动轨迹。模拟结果与文献实验数据进行了比较,吻合一致.研究结果揭示了微细颗粒在人体上呼吸道中的运动规律,可为进一步研究微细可吸入颗粒物的致病机理提供理论依据.
In order to find out motion instance of inhalational micro-particle directly threatening human health in the human airway,a more perfect three-dimensional geometry model including oral cavity,pharynx,larynx,trachea and bronchi is proposed in this paper.Based on the proposed model, micro-particle motion in the human airway during inhalation and exhalation under stable human respiration is simulated.The RNGκ-εturbulent model is used to compute airflow and particle trajectory is tracked in the frame of Lagrange.Comparison of simulation results and experimental data in the literature was conducted to validate the mathematical model;it indicates that they have good agreement.Research results discover the movement law of micro-particle in the human airway, which can offer theoretical foundation for further study of nosogenesis of inhalational micro-particle.
出处
《工程热物理学报》
EI
CAS
CSCD
北大核心
2006年第z1期225-228,共4页
Journal of Engineering Thermophysics
基金
浙江省自然科学基金重点资助项目(No.Z505050)
关键词
人体呼吸
微颗粒
运动特性
数值模拟
human respiration
micro-particle
motion characteristic
numerical simulation
